Dhanesh Patel
Dhanesh Patel is a Ph.D. student studying the virome in contexts of immunodeficiency (including in heart failure), the role of self-pMHC signaling in naïve T cells, and the heterogeneity of T cells responses to respiratory pathogens. In his spare time, Dhanesh can be found in a Brazilian jiu-jitsu or bouldering gym or sharing some laughs with friends and family.
M.Sc., Human Genetics, McGill University, QC
Supervisor: Dr. Silvia Vidal
B.Sc., Biochemistry, McGill University, QC
Awards
2024 Hugh Burke Research Award (Internal Studentship Award) from the Faculty of Medicine and Health Sciences
2024 McGill Graduate and Postdoctoral Studies Mobility Travel Award to Visit Pasteur Institute, Simon-Lorière laboratory
2024 Physiology GREAT Award; 2-week visit to Institute Pasteur, Simon-Loriere laboratory
2023 Schnabel Memorial Graduate Award (Internal Studentship Award) from the Faculty of Medicine and Health Sciences
2022 Max and Jane Childress Entrance Fellowship in Physiology
2022 Travel Award for Canadian Society of Virology 2022 Conference from Dept. of Human Genetics, McGill University
2022 Travel Award for Canadian Society of Virology 2022 Conference
Publications
Shen C, Postat J, Cerf A, Bhagrath A, Merino M, Patel D, Luo V, Abu-thuraia A, Schneider C, Sharma A, Suh WK, Ehrlicher A, Cote JF, Mandl JN. (2024). “Dock8 regulates a mechanosensitive actin redistribution that maintains immune cell cohesion and protects the nucleus during migration.” Nature Immunology, under revision, and published on bioRxiv: DOI: 10.1101/2024.07.26.605273.
Jamaleddine H, Rogers D, Perreault G, Postat J, Patel D, Mandl JN, Khadra A. (2024). “Chronic infection control relies on T cells with lower foreign antigen binding strength generated by N-nucleotide diversity.” PLOS Biology 22(2):e3002465. DOI: 10.1371/journal.pbio.3002465.
AbdElFatah T, Jalali M, Yedire SG, Hosseini II, Hamidi SV, del Real Mata C, Khan H, Jeanne O, Moakhar RS, McLean M, Patel D, Wang Z , Yousefi M, Nguyen D, Vidal SM, Liang C, Mahshid S. (2023). “Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens.” Nature Nanotechnology 18:922-932. DOI: 10.1038/s41565-023-01384-5.
Markarian NM, Galli G, Patel D, Hemmings M, Nagpal P, Berghuis AM, Abrahamyan L, Vidal SM. (2022). “Identifying Markers of Emerging SARS-CoV-2 Variants in Patients with Secondary Immunodeficiency.” Frontiers in Microbiology 13:933983. DOI: 10.3389/fmicb.2022.933983.
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